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Tesos

Tesos

  • $90.00



ACTIVE HALF-LIFE 9 days
CLASSIFICATION Psychoactive Antidepressants (SNDRI)
DOSAGE 0.25 mg - 1 mg
ACNE No
WATER RETENTION No
HBR Perhaps
HEPATOTOXICITY Low
AROMATIZATION No
MANUFACTURER Pharmacom Labs
WAREHOUSE International Warehouse 3
SUBSTANCE Tesofensine ,

Tesofensine is a novel Triple Serotonin Norepinephrine Dopamine Reuptake Inhibitor (SNDRI), which is categorized as a type of psychoactive antidepressant. It influences neurotransmitters in the brain—specifically serotonin, norepinephrine, and dopamine. Tesofensine has a significant qualitative impact on the brain, helping individuals experience greater satisfaction while eating and substantially curbing appetite. This medication was initially developed and patented by NeuroSearch A/S in Denmark for the treatment of Parkinson's and Alzheimer's diseases.

  • It acts on the central nervous system, reducing appetite, regulating dopamine receptor availability, and activating α1-adrenergic receptors.
  • Appetite reduction is noticeable within 14 days, leading to an increased sense of fullness and a diminished urge to eat.
  • It significantly enhances fat oxidation and decreases adipose tissue levels.
  • Tesofensine improves insulin sensitivity, which boosts glucose metabolism.
  • It modifies the expression and binding of dopaminergic receptors in the brain's striatum.
  • Energy expenditure increases markedly within 14 days of use.
  • The drug has a long half-life of 8-9 days and is primarily metabolized in the liver by CYP3A4 into the disalkyl metabolite M1 (NS-2360), which is the only metabolite detected in human plasma.

    • CAUTION: The listed price is for one blister containing 50 pills. If you choose to order only one blister, it will be sent without the original packaging. To receive the original box, please order two blisters (100 pills).