ACTIVE HALF-LIFE
5-12 hours
CLASSIFICATION
PDE5 inhibitor
DOSAGE
Men 25-200 mg/day
ACNE
No
WATER RETENTION
No
HBR
Possible
HEPATOTOXICITY
No
AROMATIZATION
No
MANUFACTURER
Sunrise Remedies
WAREHOUSE
International Warehouse 1
SUBSTANCE
Sildenafil
,
Malegra-100, a generic version of Viagra, is used to treat erectile dysfunction. Each tablet contains 100 mg of Sildenafil Citrate, which is adequate for addressing erectile dysfunction. Although it is a prescription medication, it can be easily purchased online without a doctor’s prescription. The drug begins to take effect within 30-45 minutes after consumption, with effects lasting for approximately 3-4 hours. Malegra-100 is available only in oral tablet form. It can interact dangerously with certain medications, and individuals with cardiovascular diseases should avoid using it.
Manufactured by Sunrise Remedies Private Limited, Malegra-100 is produced by a company that has been operating since 1995 and is based in Ahmedabad, Gujarat, India. The company specializes in both pharmaceutical and herbal products, offering a range of formulations, including capsules, tablets, liquid, and topical forms in both ayurvedic and allopathic medicine. It claims adherence to the guidelines and standards set by WHO GMP.
How It Works:The active ingredient in Malegra, Sildenafil Citrate, effectively inhibits phosphodiesterase Type 5 (PDE5) in the corpus cavernosum. This action helps prevent the breakdown of cyclic guanosine monophosphate (cGMP). As levels of nitric oxide (NO) increase in the corpus cavernosum, it binds to cGMP receptors, enhancing cGMP levels. This process relaxes the smooth muscles in the helicine arteries, allowing increased blood flow to the penis, which results in a firm erection.
Malegra-100 provides a reliable treatment for erectile dysfunction. The sildenafil component boosts blood flow to the penis, enhancing erection firmness and duration. Its effects last around 4-6 hours, making it an effective option for addressing erectile dysfunction. While the medication can fully address the condition, doses taken based on occasion may not offer long-lasting results.
For best results, Malegra-100 should be taken by a sexually stimulated man 25-30 minutes before anticipated intercourse. It is recommended to take no more than one tablet a day. The effects of a single dose can last approximately five to six hours, and in some instances, may extend up to ten hours.
Side Effects:Common side effects associated with sildenafil citrate include skin flushing, nausea, gastrointestinal discomfort, and dizziness. Some users may experience swelling in the ankles and feet or difficulties sleeping. In certain cases, users might face serious side effects such as hearing loss. High doses can lead to unwanted, prolonged, and painful erections, which may also result in pain in other areas like the chest, jaw, and left arm.
Drug Interactions:Caution is advised for individuals taking protease inhibitors, as these can impede the metabolism of sildenafil, increasing its effects and side effects. Other medications that may interact with Malegra include the antibiotic Erythromycin and the H2 blocker Cimetidine, used for peptic ulcers. It is also advised not to combine Malegra-100 with alpha-blockers, as this combination may lead to dangerously low blood pressure, despite no documented cases existing. Additionally, Malegra is known to interact with nitrates, which can cause severe hypotension if used together.