CLASSIFICATION
Glycoprotein hormones, alpha polypeptide
DOSAGE
500-3000IU 1-3 times/week
ACNE
Possible
WATER RETENTION
No
HBR
No
HEPATOTOXICITY
No
AROMATIZATION
No
MANUFACTURER
MSD
WAREHOUSE
International Warehouse 2
SUBSTANCE
Human Chorionic Gonadotropin
,
Pregnyl 1500IU is an injectable medication produced by MSD, containing Human Chorionic Gonadotropin (hCG) as its active ingredient. This hormone is typically generated during pregnancy by the developing placenta following conception, and subsequently by the syncytiotrophoblast component of the placenta. Among its various applications, hCG is known to suppress appetite and promote the body's utilization of fat as energy. It is also employed to induce ovulation, treat infertility in women, and enhance sperm production in men. Bodybuilders often incorporate it into steroid cycles and post-cycle therapy to maintain gains and boost testosterone levels.
Bodybuilders and athletes use Pregnyl at the conclusion of an anabolic steroid cycle to help prevent muscle tissue breakdown and aid in restoring normal testicular function. Following periods of anabolic steroid use, an athlete's testes may shrink, but Pregnyl is effective in returning them to their normal size. In conjunction with a very low-calorie diet, athletes can shed excess fat while preserving muscle. Women may also utilize Pregnyl along with a low-calorie diet for fat loss.
Typical dosing of Pregnyl during a cycle ranges from 500iu to 3000iu weekly, administered 1 to 3 times per week. More frequent injections can help maintain stable blood levels, whereas a single larger dose may elevate estrogen levels due to the aromatization of testosterone, possibly leading to gynecomastia. Some sources indicate that certain bodybuilders have used up to 6000iu over a 6-day period, but this carries risks and should be tailored to individual circumstances. For post-cycle therapy, Pregnyl is usually given in smaller doses, around 250 to 500iu each day for 2 to 3 weeks, as this amount suffices to initiate the recovery from testicular atrophy. When starting an hCG regimen, bodybuilders should continue it for 2 to 3 weeks, ensuring at least a month off before beginning another cycle. Pregnyl can be effectively paired with Clomid or Nolvadex during post-cycle therapy, with continued use after hCG is discontinued. It is advisable to initiate an hCG program near the end of a steroid cycle, ideally in the last week.
Potential serious side effects of Pregnyl include severe pelvic pain, swelling in the limbs, abdominal pain and swelling, difficulty breathing, weight gain, diarrhea, nausea, or vomiting. Common side effects may consist of headaches, feelings of restlessness or irritability, mild swelling or water retention, depression, breast tenderness or swelling, and localized pain or irritation at the injection site. In boys, Pregnyl can trigger early puberty signs, such as voice deepening, pubic hair growth, and an increase in acne or perspiration.