Cardio Agent (GW-501516)

ACTIVE HALF-LIFE 20-24 hours
CLASSIFICATION PPAR-delta agonist
DOSAGE 20 mg/day
ACNE No
WATER RETENTION No
HBR No
HEPATOTOXICITY No
AROMATIZATION No
MANUFACTURER Euro-Pharmacies - US
WAREHOUSE USA Warehouse 3
SUBSTANCE Cardarine ,

Although many people classify cardarine (GW 501516) as a SARM, it is more accurately described as a PPAR-delta agonist (peroxisome proliferator-activated receptor). Typically marketed as a SARM, it’s akin to how tomatoes, though botanically fruits, are commonly treated as vegetables. Cardarine was designed to confer health benefits by activating the same biological pathways that the body uses during exercise. This article will cover all the essential information about this effective compound in straightforward language.

Cardarine emerged from research collaborations between GSK and Ligand Pharma that began in the early 1990s. Notably, the compound underwent phase 1 clinical trials in 2000 for addressing lipid issues but was discontinued in 2008. Today, however, it remains a research chemical, leveraged by athletes for enhancing performance and promoting fat loss.

Cardarine was primarily developed to combat obesity, diabetes, lipid issues, and cardiovascular health concerns. Individuals who undergo blood tests might find that cardarine significantly improves their lipid profiles and cholesterol levels.

Athletes across various sports utilize cardarine. Endurance competitors, for example, can enhance their stamina by combining this PPAR agonist with the AMP analog drug AICAR or using it independently. This results in the ability to maintain higher RPMs during races without reaching their maximum heart rates. Consequently, runners, cyclists, and swimmers can push their limits while avoiding fatigue, making this combination an excellent asset in endurance events. From personal experience, I've witnessed that using cardarine prior to a race can shave off 30 to 45 seconds from a 5K time.

Bodybuilders can benefit from cardarine in two primary ways:

When weightlifters perform sets, their heart rates can soar, but cardarine allows many athletes to extend their performance by completing additional repetitions before reaching failure. Furthermore, it reduces the necessary rest time between sets, and bodybuilders who incorporate cardio post-weight training will also reap these benefits.

Cardarine gained notoriety in the lead-up to the 2008 Beijing Olympic Games, being significantly misused by athletes before it was banned by WADA in 2009, labeled as a ‘hormone and metabolic modulator.’

Several cyclists have been caught using cardarine; for instance, Russian cyclist Valery Kaykov received a suspension, and in 2013 Miguel Ubeto from Venezuela was removed from the Lampre team. Last year, notably, Elena Lashmanova of Russia, who holds the world record for the 20M race walk, tested positive for cardarine.

When it comes to combating obesity, cardarine addresses metabolic issues in obese and pre-diabetic individuals by promoting fatty acid oxidation. Specifically, it enhances fat burning through increased glucose absorption in muscle tissue, shifting the body’s metabolism to utilize fat for energy rather than depleting muscle or carbohydrates. Remarkably, this occurs without lowering blood sugar levels as diabetes medications do. Studies have shown that mice on high-fat diets maintained fat loss, reinforcing cardarine’s effectiveness in preventing obesity.

Here are a few recommended ways to combine cardarine:

Pair cardarine with AICAR and/or Equipoise for an enhanced endurance stack that can elevate your performance.

Stacking cardarine with S4 (Andarine) creates a powerful cutting stack.

If using moderate doses of anabolic steroids or potent compounds like trenbolone, cardarine can help manage lipids and improve endurance, making it a valuable addition for those using trenbolone.

Since cardarine is non-hormonal, it does not cause suppression, making it safe for use to maintain fat loss and enhance workouts between cycles.

For body recomposition, cardarine pairs effectively with S4 and MK-2866.

While side effects from cardarine are rare, it is crucial to use it at the proper dosage and to cycle on and off safely. As it is not a hormone, there are no concerns regarding suppression or the need for PCT.

The standard dosage for both men and women is 20 milligrams (mg) per day. The half-life of GW501516 ranges from 20 to 24 hours, allowing for a once-daily dose. Some athletes take the full 20 mg an hour before workouts, while others prefer to split the dosage into two parts, one in the morning and one in the evening.

It is recommended to administer the liquid by squirting it into your mouth, swallowing, and then washing it down with juice or water.