Duspatalin 100

ACNE No
WATER RETENTION No
HBR No
HEPATOTOXICITY No
AROMATIZATION No
MANUFACTURER Abbott
WAREHOUSE International Warehouse 2
SUBSTANCE Mebeverine Hydrochloride ,

Duspatalin is indicated for the management of irritable bowel syndrome and related conditions such as chronic irritable colon, spastic constipation, mucous colitis, and spastic colitis. It is used for symptomatic relief of abdominal pain, cramps, nonspecific diarrhea, and flatulence. Additionally, it addresses gastrointestinal spasms resulting from organic diseases, including diverticulitis, gastritis, duodenitis, esophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcers, gallbladder issues, hiatus hernia, and gastrointestinal tract inflammation.

Duspatalin is primarily used to alleviate symptoms of irritable bowel syndrome, which manifests as abdominal cramps, gas, bloating, and alterations in bowel habits. It also provides relief for various conditions associated with spasm and pain in both the small and large intestines.

Each capsule contains 100 mg of Mebeverine. The formulation includes several excipients: Capsule Content (Granules) comprises magnesium stearate, polyacrylate dispersion (30%), talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion (30%), and glycerol triacetate. The Capsule Shell is made of gelatin and titanium dioxide (E171). The printing ink consists of shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, and potassium hydroxide.

For adults, the recommended dosage is 1 capsule taken twice daily (one in the morning and one in the evening).

For the elderly and those with renal or hepatic impairment, no specific dosage adjustments are required as there have been no posology studies conducted in these groups. Additionally, no particular risks have been identified from existing post-marketing data.

If one or more doses are missed, patients should resume with the next scheduled dose, avoiding extra doses to make up for missed ones.

Capsules should be taken whole with at least 100 mL of water and must not be chewed, as the coating is designed for sustained release.

No formal interaction studies, except those with alcohol, have been conducted. Research indicates that Duspatalin does not interact negatively with ethanol in both in vitro and in vivo settings.

There are no known incompatibilities.

While adverse reactions are uncommon, some patients have reported gastrointestinal disturbances, dizziness, headaches, insomnia, loss of appetite, and increased heart rate.

Duspatalin is contraindicated in individuals who have hypersensitivity to Mebeverine hydrochloride or any of its excipients.